dna

The UK’s first approval of a CRISPR gene therapy is a big deal

The UK’s first approval of a CRISPR gene therapy is a big deal 348 522 Jamie Metzl

It’s a huge deal that UK regulators today granted their first-ever approval for a gene therapy created using CRISPR. Casgevy, developed by the companies Vertex and CRISPR Therapeutics, treats the…

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Our WHO Expert Committee Report on Human Genome Editing

Our WHO Expert Committee Report on Human Genome Editing 243 208 Jamie Metzl

As you may know, I’ve had the great honor of serving as a member of the World Health Organization expert advisory committee on human genome editing, created by WHO Director…

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Our Best Values Must Guide Our Most Powerful Technologies

Our Best Values Must Guide Our Most Powerful Technologies 279 181 Jamie Metzl

Soon after a series of incredible discoveries almost five decades ago launched the era recombinant DNA (later renamed genetically modified organisms, or GMOs), some of the world’s leading scientists and…

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Inviting You to a Genetic Engineering Dinner Party (*)

Inviting You to a Genetic Engineering Dinner Party (*) 284 284 Jamie Metzl

I am inviting you to a dinner party – where you are the host. You can invite whomever you’d like: your family, friends, co-workers, book club members, etc. The preparation…

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Gene editing of human embryos

Gene editing of human embryos 600 220 Jamie Metzl

You may have seen today’s New York Times article describing how scientists have for the first time successfully edited genes in unimplanted human embryos. As the article notes: “Scientists at Oregon…

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Homo Sapiens 2.0? We Need a Species-Wide Conversation on the Future of Human Genetic Enhancement

Homo Sapiens 2.0? We Need a Species-Wide Conversation on the Future of Human Genetic Enhancement 230 219 Jamie Metzl

In my article in TechCrunch, released today, I call for a species-wide conversation on the future of human genetic enhancement. Such a dialogue has never before been carried out. We…

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NIH Restrictions on Chimera Research a Mistake

NIH Restrictions on Chimera Research a Mistake 150 150 Jamie Metzl

In a letter published today in Science, leading researchers argue against the National Institute of Health’s recent moratorium on funding for scientists implanting human stem cells into non-human embryos (see…

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Has the Genetic Arms Race Begun?

Has the Genetic Arms Race Begun? 150 150 Jamie Metzl
Articles in Nature yesterday and in today’s New York Times describe the controversial recent announcement by a Chinese researcher that he has used cutting edge precision gene editing techniques (CRISPR-cas9) on non-viable human embryos.  It is rumored that the results of more research like this will be announced from China in the coming months. Every day we are receiving more evidence like this that the human genetic revolution, with its massive scientific, ethical, political, and national security implications, has already begun. read more

Would I Genetically Enhance My Own Children?

Would I Genetically Enhance My Own Children? 150 150 Jamie Metzl
When someone at a Los Angeles book event asked me a personal question, I was already disarmed, exposed, and predisposed to a more personal answer. “Would you genetically enhance your own children?” read more

Books as Sacred Objects

Books as Sacred Objects 150 150 Jamie Metzl

I hope you’ll have a look at my new bookreporter.com piece on books as sacred objects. “As a great lover of books, I felt myself not only drawn to their words,…

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